Prevalensi Servisitis Gonore pada Wanita Hamil di Rumah Sakit Khusus Ibu dan Anak Kota Bandung Tahun 2015

Armina Haramaini, Rachmatdinata Rachmatdinata, Rasmia Rowawi


Gonore adalah infeksi menular seksual (IMS) yang disebabkan oleh Neisseria gonorrhoeae (N. gonorrhoeae). Salah satu manifestasi klinis gonore pada wanita adalah servisitis yang sebagian besar asimtomatik dan bila tidak diterapi servisitis gonore pada wanita hamil dapat menimbulkan komplikasi pada ibu, kehamilan, dan janin. Tujuan penelitian ini mengetahui prevalensi servisitis gonore pada wanita hamil di Rumah Sakit Khusus Ibu dan Anak (RSKIA) Kota Bandung tahun 2015. Penelitian ini merupakan penelitian deskriptif dengan desain potong lintang. Subjek penelitian adalah 100 wanita hamil dengan bahan pemeriksaan adalah apus endoserviks. Diagnosis servisitis gonore ditegakkan jika pada sedian apus gram ditemukan jumlah polimorfonuklear (PMN) >30/lapang pandang besar (lpb) dan diplokokus gram negatif intraseluler, serta hasil PCR N. gonorrhoeae positif. Hasil PCR N. gonorrhoeae pada seluruh subjek penelitian negatif. Namun, 41 orang (41%) subjek penelitian ditemukan jumlah PMN >30/lpb, tanpa diplokokus gram negatif intraseluler, dan didiagnosis servisitis nongonore. Simpulan penelitian ini, yaitu prevalensi servisitis gonore pada wanita hamil di RSKIA Kota Bandung tahun 2015 adalah 0%. Hasil tersebut diduga karena karakteristik sebagian besar subjek penelitian tidak termasuk ke dalam risiko tinggi mengidap IMS.



Gonnorhea is a sexually transmitted infection (STI) that is caused by Neisseria gonorrhoeae. One of the clinical manifestation of gonnorhea in female is cervicitis, that mostly asymptomatic. If it is left untreated, gonnorheal cervicitis in pregnant woman will cause complication to the mother, pregnancy, and fetus. The aim of this study was to know the prevalence of gonnorheal cervicitis in pregnant woman in mother and children hospital (RSKIA) Bandung in year 2015. The study design was cross sectional and descriptive. Subjects were 100 pregnant women, which was taken the sample from endocervical swab. Diagnosis of gonnorheal cervicitis was established if more than 30/high power field (hpf) polymorphonuclear (PMN) and extra or intracellular gram negative diplococcus found from gram staining, also positive PCR result for N. gonorrhoeae. The result of PCR in all subjects were negative. But, there were 41 subjects with PMN more than 30/hpf, with no intra or extra cellular diplococcus found, and those subjects were diagnosed as non gonnorheal cervicitis. Conclusion of this study was that the prevalence of gonorrheal cervicitis of pregnant woman in RSKIA Bandung in year 2015 is 0%. This result was suggested due to the subjects characteristics in this study mostly were not high risk for STI.


Gonorrheal cervicitis; kehamilan; pregnancy; prevalence; prevalensi; servisitis gonore


Bala M, Mullick JB, Muralidhar S, Kumar J, Ramesh V. Gonorrhoea prevalence & co-infection with other ulcerative, non-ulcerative sexually transmitted & HIV infection in a regional STD Centre. Indian J Med Res. 2011;133:346–9.

Global prevalence and incidence of selected curable sexually transmitted infections. WHO. Geneva: Departement of Communicable Diseases Surveillance and Response; 2008.

Hook EW, Handsfield HH. Gonococcal infections in adults. Dalam: Holmes KK, Sparling PF, Stamm WE, Piot P, Wasserheit JN, Corey L, penyunting. Sexually transmitted disease. Edisi ke-4. New York: McGraw-Hill; 2008. hlm. 627–45.

Walker CK, Sweet RL. Gonorrhea infection in women: prevalence, effects, screening, and management. Int J W Health. 2011;3:197–206.

Romoren M, Sundby J, Velauthapillai M, Rahman M. Chlamydia and gonorrhea in pregnant Bastwana women: time to discard the syndromic approach?. BMC Infec Dis. 2007;7:27.

Diclemente RJ, Wingood GM, Crosby RA, Rose E. A descriptive analysis of STD prevalence among urbant pregnant African-American teens: data from a pilot study. J Adolescent Health. 2004;34:376–83.

Aboyeji AP, Nwabuisi C. Prevalence of sexually transmitted disease among pregnant women in Illorin, Nigeria. J Obstet Gynecol. 2003;23:637–9.

Puspitasari D. Prevalensi servisitis gonore pada ibu hamil di Poliklinik Kebidanan RSP Dr. Hasan sadikin Bandung berdasarkan pemeriksaan kultur [tesis]. Bandung: Fakultas Kedokteran Universitas Padjadjaran; 1998.

Bignell C. 2009 European (IUSTI/WHO) guideline on the diagnosis and treatment og gonorrhea in adults. Int J STD AIDS. 2009:453–7.

Whiley DM, Tapsall JW, Sloots TP. Nucleic acid amplification testing for Neisseria gonorrhoeae: an ongoing challenge. J Mol Diagn. 2006;8(1):3–15.

Pusat Data dan Informasi PERSI. Rumah Sakit Astana Anyar [diunduh 6 September 2014]. Tersedia dari:

Moaiedmohseni S, Bashardoost L, Abbasi M. Cervicovaginal infections during third trimester of pregnancy. J Fam Repr Health. 2012;6(1):11–5.

Shin J, Donegan SP, Heeren TC, Greenberg M. Transmission of Chlamydia trachomatis and Neisseria gonorrhoeae among men with urethritis and their female sex partners. J Infect Dis. 1998;178:1707–12.

Edem A, Ntekpe M, Umoekam N. Prevalence of syphilis and gonorrhea in patient attending General Hospital, Calabar, Nigeria. Int J Modern Biol Med. 2013;4(3):155–68.

Solomon MM, Smith MJ, Rio CD. Low educational level: a risk factor for sexually transmitted infections among commercial sex workers in Quito, Ecuador. Int J STD AIDS. 2008;19:264–7.

Nyarko C, Unson C, Koduah M. Risk factors of sexually transmitted infections (stis) among men and women in a mining community in western Ghana: a study of lifetime occurrence. Int J Scie Technol. 2014;3(12):361–9.

Situmorang A. Adolescent Reproductive Health in Indonesia. 2003:1–20.

Braddick MR, Achola JO, Mirza NB. Towards developing a diagnostic algorithm for Chlamydia trachomatis and Neisseria gonorrhoeae cervicitis in pregnancy. Genito Urin Med. 1990;66:62–5.

Hassanzadeh P, Mardaneh J, Motamedifar M. Coventional agar based culture method, and nucleic acid amplification test (NAAT) of the cppB gene for detection of Neisseria gonorrhoeae in pregnant women endocervical swab specimens. Ir R Cresc Med J. 2013;15(3):207–11.

Moleka RK, Smith JS, Atibu J. Low prevalence of HIV and other selected sexually transmitted infections in 2004 in pregnant women from Kinshasa, the Democratic of the Congo. Epidemiol Infect. 2008;136:1290–6.

Bakhtiari A, Firoozjahi AR. The prevalence of gonococcal infection in non pregnant women. Iranian J Pub Health. 2007;36(2):64–7.

Thammlangsy S, Sihavong A, Pbouthavane T, Suyubonthavony K. The prevalence of lower genital tract infections among antenatal care (ANC) clinics patient in two centrals hospitals, Viantiene, Lao People ‘s Democratic Republic. J Trop Med Public Health. 2006;37(1):190–9.

Magriples U, Copel JA. Can risk factor assessment replace universal screening for gonorrhea and chlamydia in the third trimester?. Am J Perinatol. 2001;18(8):65–8.

Berggren EK, Patchen L. Prevalence of Chlamydia trachomatis and Neisseria gonorrhoeae and repeat infection among pregnant urban adolescents. Sex Transm Dis. 2011;38(3):172–4.

Usanga V, Bassey LA, Etoh PI, Udoh S, Ani F, Archibong E. Prevalence of sexually transmitted disease in pregnant and non pregnant women in Calabar, cross River State, Nigeria. Intern J Gynecol. 2009;14(2).

Wangnapi RA, Soso S, Unger HW, Sawera C. Prevalence and risk factors for Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonasvaginalis infection in pregnant women in Papua New Guinea. Sex Transm Infect. 2015 May;91(3):194–200.

Venkatesh KK, Straten A, Mayer KH, Blanchard K. African women recently infected with HIV1 and HSV2 have increased risk of acquiring Chlamydia trachomatis and Neisseria gonorrhoeae in the methods for improving reproductive health in Africa Trial Sex Transm Infect. 2011;38(6):562–70.

Blatt AJ, Lieberman JM, Hoover DR, Kaufman HW. Chlamydial and gonococcal testing during pregnancy in the United States. Am J Obstet Gynecol. 2012;207:55.e1–8.

Stary A. Sexually transmitted infections. Dalam: Bolognia JL, Jorizzo JL, Rapini RP, penyunting. Dermatology. Edisi ke-2. Edinburgh: Mosby Elsevier; 2008. hlm. 1239–61.

Jackson SL, O’Connell NG, Borzelleca JF. Cervicitis as a clinical indicator of gonococcal and Chlamydia infections in pregnancy. Infect Dis Obs Gyn. 1995;3:184–8.

Repke JT, Berlin L, Spence M, Horn J, MacKenzie E. Reproducibility of diagnosis of cervicitis in pregnancy. Am J Perinatol. 1988;5(3):242–6.

Holmes KK, Stamm WE, Sobel JD. Lower genital tract infection syndromes in women. Dalam: Holmes KK, Sparling PF, Stamm WE, Piot P, Wasserheit JN, Corey L, dkk., penyunting. Sexually transmitted diseases. Edisi ke-4. New York: McGraw-Hill; 2008. hlm. 987–1010.

Hillier SL, Khron MA, Nugent RP, Gibbs RS. Characteristics of three vaginal flora patterns assessed by Gram stain among pregnant woman. Am J Obstet Gynecol. 1992;166(3):938–44.

Lurie S, Asaala H, Harari OS, Golan A, Sadan O. Uterine cervical non-gonococcal and non-chlamydial bacterial flora and its antibiotic sensitivity in woman with pelvic inflammatory disease: did it vary over 20 years?. Isr Med Assoc J. 2010;12:747–9.

Dyck VE, Ieven M, Pattyn S, Van DL, Laga M. Detection of Chlamydia trachomatis dan Neisseria gonorrhoeae by enzyme immunoassay, culture, and three nucleic acid amplification test. J Clin Microbiol. 2001;39:1751–6.


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