Kondiloma Akuminata di Daerah Anus yang Disebabkan oleh Infeksi Human Papilloma Virus Tipe 6, 11, dan 16 pada Seorang Laki Suka Laki dengan HIV Positif

Pati Aji Achdiat, Tony S. Djajakusumah, Rachmatdinata Rachmatdinata

Abstract


Human papilloma virus (HPV) merupakan salah satu penyebab infeksi menular seksual terbanyak di seluruh dunia. Kondiloma akuminata (KA) merupakan salah satu manifestasi klinis infeksi HPV yang paling sering ditemukan. Risiko terinfeksi virus HPV multipel lebih tinggi pada penderita HIV, sedangkan risiko terinfeksi tipe ganas lebih tinggi pada laki suka laki (LSL). Dilaporkan satu kasus KA di daerah anus yang disebabkan oleh infeksi HPV tipe 6, 11, dan 16 pada seorang LSL dengan HIV positif. Diagnosis ditegakkan berdasarkan gambaran klinis yang karakteristik berupa papula dan plak verukosa berbentuk seperti bunga kol. Hasil pemeriksaan histopatologis menunjang diagnosis KA namun tidak menunjukkan tanda-tanda keganasan. Pasien diberikan terapi bedah listrik dan trikloroasetat (TCA) 80% topikal. Faktor risiko KA multipel pada pasien ini kemungkinan disebabkan jumlah pasangan seksual yang banyak, LSL, dan infeksi HIV dengan hitung CD4 382 sel/uL. Hasil serotyping menunjukkan penyebab KA adalah HPV tipe 6, 11, dan 16. Pasien disarankan untuk melakukan skrining sitologi setiap tahun.

 

CONDYLOMATA ACUMINATA IN THE ANAL REGION CAUSED BY TYPE 6, 11, AND 16 HUMAN PAPILLOMA VIRUS INFECTION IN HIV POSITIVE MAN WHO HAVE SEX WITH MAN

Human papiloma virus (HPV) is the most common cause of sexually transmitted infection worldwide. Condyloma acuminata is the most common form of HPV infection. In HIV patient, the risk to get multiple HPV infection is increased, while in man who have sex with man (MSM), the risk to develop into malignancy is even geater. A case of condyloma acuminata (CA) in the anal region caused by HPV type 6, 11, and 16 in MSM with HIV infection was reported. Diagnosis was established based on typical clinical feature presented as verrucous papules and plaques resembling cauliflower. Histopathological result supported the diagnosis of CA without sign of malignancy. Patient was treated with electrosurgery and topical 80% TCA solution. The risk factors for CA in this patient possibly were the high number of sexual partners, MSM status, and HIV infection with CD4 count of  382 cell/uL. Serotyping result revealed that CA in this patient was caused by HPV type 6, 11, and 16. The patient was suggested to undergo cytologic screening analysis every year forwards.


Keywords


Condyloma acuminata; HIV; infeksi HPV multipel; kondiloma akuminata; LSL; MSM; multiple HPV infection



DOI: https://doi.org/10.29313/gmhc.v1i1.1515

pISSN 2301-9123 | eISSN 2460-5441


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