Correlation of Knee Osteoarthritis Patients' Characteristics and the Results of 30-Second Sit-to-Stand Test with Quality of Life

Susanti Dharmmika, Satryo Waspodo, Ami Rachmi, Sigit Gunarto, Fatimah Az Zakiyah, Syachla Dhiena Qothrunnada, Ayyas Robbani, Nabila Zulfa Alfina


Pain, joint stiffness, and difficulty performing activities like rising from sitting to standing are signs and symptoms of knee osteoarthritis (OA). These conditions are risk factors for limited mobility and lower quality of life. Knee OA is closely associated with age, women, obesity, and other characteristics. The study's objectives were to determine the correlation of knee OA patients' characteristics with functional mobility using the 30-second sit-to-stand test (30STS) and the correlation of functional mobility with quality of life using the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) Index. The research method was descriptive-analytic cross-sectional using medical records of 73 knee OA patients at the Medical Rehabilitation Clinic at Soreang Hospital, Muhammadiyah Hospital, Al Islam Hospital, Al-Ihsan Regional General Hospital West Java Province, Bandung, from March until August 2021. Patients' characteristics such as age (p=0.02), onset (p=0.01), OA grade (p=0,03), and knee deformity (p=0.04 ) have a negative correlation with functional mobility based on 30STS as well as functional mobility had a negative correlation with various aspects of quality of life, such as pain (p=0.03), stiffness (p=0.02), and functional limitation (p=0.00) subscales based on WOMAC index. Age, the onset of disease, OA grade, and knee deformity significantly correlate to functional immobility. Based on the WOMAC index, functional immobility correlates with the patient's quality of life.


30-second sit-to-stand test; functional mobility; knee osteoarthritis; quality of life; WOMAC index

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Cui A, Li H, Wang D, Zhong J, Chen Y, Lu H. Global, regional prevalence, incidence and risk factors of knee osteoarthritis in population-based studies. EClinicalMedicine. 2020;29–30:100587.

Badan Penelitian dan Pengembangan Kesehatan, Kementerian Kesehatan Republik Indonesia. Laporan Nasional Riskesdas 2018. Jakarta: Lembaga Penerbit Badan Penelitian dan Pengembangan Kesehatan; 2019.

Badan Penelitian dan Pengembangan Kesehatan, Kementerian Kesehatan Republik Indonesia. Laporan Provinsi Jawa Barat Riskesdas 2018. Jakarta: Lembaga Penerbit Badan Penelitian dan Pengembangan Kesehatan; 2019.

Tsekoura M, Anastasopoulos K, Kastrinis A, Dimitriadis Z. What is most appropriate number of repetitions of the sit-to-stand test in older adults: a reliability study. J Frailty Sarcopenia Falls. 2020;05(04):109–13.

Verlaan L, Boekesteijn RJ, Oomen PW, Liu WY, Peters MJM, Witlox MA, et al. Biomechanical alterations during sit-to-stand transfer are caused by a synergy between knee osteoarthritis and obesity. Biomed Res Int. 2018;2018:3519498.

Bohannon RW, Bubela DJ, Magasi SR, Wang YC, Gershon RC. Sit-to-stand test: performance and determinants across the age-span. Isokinet Exerc Sci. 2010;18(4):235–40.

Alghadir AH, Anwer S, Iqbal A, Iqbal ZA. Test-retest reliability, validity, and minimum detectable change of visual analog, numerical rating, and verbal rating scales for measurement of osteoarthritic knee pain. J Pain Res. 2018;11:851–6.

WHO Expert Consultation. Lancet. Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. 2004;363(9403):157–63.

World Health Organisation. Waist circumference and waist-hip ratio: report of a WHO expert consultation, Geneva, 8–11 December 2008. Geneva: World Health Organisation; 2011 [cited 2022 July 11]. Available from:

Woolacott NF, Corbett MS, Rice SJC. The use and reporting of WOMAC in the assessment of the benefit of physical therapies for the pain of osteoarthritis of the knee: findings from a systematic review of clinical trials. Rheumatology (Oxford). 2012;51(8):1440–6.

Dahlan MS. Statistik untuk kedokteran dan kesehatan: deskriptif, bivariat, dan multivariat. 2016. 6th Edition. 11th Printing. Jakarta: Epidemiologi Indonesia; 2021.

McCarthy I, Hodgins D, Mor A, Elbaz A, Segal G. Analysis of knee flexion characteristics and how they alter with the onset of knee osteoarthritis: a case control study. BMC Musculoskelet Disord. 2013;14:169.

Blagojevic M, Jinks C, Jeffery A, Jordan KP. Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis. Osteoarthritis Cartilage. 2010;18(1):24–33.

Heidari B. Knee osteoarthritis prevalence, risk factors, pathogenesis and features: Part I. Caspian J Intern Med. 2011;2(2):205–12.

Martin JA, Buckwalter JA. Roles of articular cartilage aging and chondrocyte senescence in the pathogenesis of osteoarthritis. Iowa Orthop J. 2001;21:1–7.

Hsu H, Siwiec RM. Knee osteoarthritis. In: StatPearls [Internet]. Treasure Island (FL): StatPearls; 2022 [cited 2022 July 12]. Available from:

Abbate LM, Stevens J, Schwartz TA, Renner JB, Helmick CG, Jordan JM. Anthropometric measures, body composition, body fat distribution, and knee osteoarthritis in women. Obesity (Silver Spring). 2006;14(7):1274–81.

Centers for Disease Control and Prevention. Assessment 30-second chair stand [Internet]. Atlanta: Centers for Disease Control and Prevention; 2017 [cited 2022 July 15]. Available from:

Alcazar J, Kamper RS, Aagaard P, Haddock B, Prescott E, Ara I, et al. Relation between leg extension power and 30-s sit-to-stand muscle power in older adults: validation and translation to functional performance. Sci Rep. 2020;10(1):16337.

Roebroeck ME, Doorenbosch CAM, Harlaar J, Jacobs R, Lankhorst GJ. Biomechanics and muscular activity during sit-to-stand transfer. Clin Biomech (Bristol, Avon). 1994;9(4):235–44.

Anan M, Shinkoda K, Suzuki K, Yagi M, Ibara T, Kito N. Do patients with knee osteoarthritis perform sit-to-stand motion efficiently? Gait Posture. 2015;41(2):488–92.

Stevens J, Katz EG, Huxley RR. Associations between gender, age and waist circumference. Eur J Clin Nutr. 2010;64(1):6–15.

Turcot K, Armand S, Fritschy D, Hoffmeyer P, Suvà D. Sit-to-stand alterations in advanced knee osteoarthritis. Gait Posture. 2012;36(1):68–72.

Hawamdeh ZM, Al-Ajlouni JM. The clinical pattern of knee osteoarthritis in Jordan: a hospital based study. Int J Med Sci. 2013;10(6):790–5.

Kocak FU, Unver B, Karatosun V, Bakirhan S. Associations between radiographic changes and function, pain, range of motion, muscle strength and knee function score in patients with osteoarthritis of the knee. J Phys Ther Sci. 2009;21(1):93–7.

Schmitz RJ, Harrison D, Wang HM, Shultz SJ. Sagittal-plane knee moment during gait and knee cartilage thickness. J Athl Train. 2017;52(6):560–6.

Frykberg GE, Häger CK. Movement analysis of sit-to-stand–research informing clinical practice. Phys Ther Rev. 2015;20(3):156–67.

Jones CJ, Rikli RE, Beam WC. A 30-s chair-stand test as a measure of lower body strength in community-residing older adults. Res Quart Exerc Sport. 1999:70(2):113–9.

Lord SR, Murray SM, Chapman K, Munro B, Tiedemann A. Sit-to-stand performance depends on sensation, speed, balance, and psychological status in addition to strength in older people. J Gerontol A Biol Sci Med Sci. 2002;57(8):M539–43.

Karsten S, Limena S, Phandu M. Translation, adaptation, and validation of Western Ontario and Mcmaster Universities osteoarthritis index (WOMAC) for indonesian. JOTI. 2019;2(3):17–26.


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